This paper examines trends in the productivity of the pharmaceutical sector over the past three decades. Motivated by Ricardo’s insight regarding demand-driven productivity in settings of scarce resources, we examine the industry’s aggregate R&D production function. Using exogenous demand shocks to instrument investments, we find that demand growth explains roughly half of R&D growth and amongst this demand-induced R&D, the industry’s returns to scale have been very stable while total factor productivity has declined significantly. Suggestive evidence based on these estimates is in line with Ricardo’s prediction that productivity and rents are endogenous to demand.

More on this topic

BFI Working Paper·May 5, 2026

Retrospective Versus Prospective Meritocracy

Steven Durlauf
Topics: Uncategorized
BFI Working Paper·Mar 17, 2026

Quantum Bayesian Inference: An Exploration

Jon Frost, Carlos Madeira, Yash Rastogi, and Harald Uhlig
Topics: Uncategorized
BFI Working Paper·Feb 23, 2026

Multidimensional Signaling and the Rise of Cultural Politics

Daron Acemoglu, Georgy Egorov, and Konstantin Sonin
Topics: Uncategorized