In Latin America—the world’s most unequal region—non-white rural populations disproportionately suffer from Chagas disease, a neglected tropical disease (NTD) that causes weeks of acute symptoms and can lead to chronic heart problems decades later. We demonstrate that Brazil’s post-1983 campaign to eliminate the transmission of this disease significantly reduced (racial) income inequality, the intergenerational transmission of low human capital, and burdens on the world’s largest government-run health care system. Exploiting the pre-treatment presence of Chagas disease’s main vector, we find that controlling this NTD increased municipalities’ GDP per capita by 11.1% and reduced their Gini coefficients by 1.1% in the long run. Furthermore, averting childhood exposure to Chagas disease increased the share of non-white adults with above-median incomes by 1.4 percentage points (p.p., or 2.8%) and their children’s literacy rates by 0.4 p.p. (0.5%). Coinciding with the expected reduction in chronic heart problems, we also find that public spending on circulatory disease hospital care declined by 16%, contributing to a 24% internal rate of return and an infinite marginal value of public funds. These results suggest that NTD control can improve the economic and fiscal health of developing countries while mitigating (racial) disparities and intergenerational cycles of poverty.

More on this topic

BFI Working Paper·Oct 7, 2025

Human Capital Accumulation Across Space

Klaus Desmet, Dávid Krisztián Nagy, and Esteban Rossi-Hansberg
Topics: Development Economics
BFI Working Paper·Sep 18, 2025

The Five Shanghai Themes

Harald Uhlig
Topics: Economic Mobility & Poverty, Energy & Environment, Financial Markets, Health care
BFI Working Paper·Aug 26, 2025

Religion in Emerging and Developing Regions

Sara Lowes, Benjamin Marx, and Eduardo Montero
Topics: Development Economics